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Summary Despite lots of research and lots of buzz the existing scientific data doesnt support the vast majority of claims that common MTHFR variants impact human health

A collagen powder, a prescription GLP-1 medication and an injectable peptide sold through a wellness website may all fall under the peptide category, even though they carry very different levels of evidence and oversight

Medications that can enhance the activity of insulin (so-called incretin mimetics) can help to overcome insulin resistance caused by SGAs (and potentially by other psychotropic medications) and essentially lead to weight loss through enhanced fuel efficiency. Metformin, typically dosed up to 1,000 mg twice daily with meals, has increasingly become recognized as a first-line strategy to attenuate weight gain and glycemic dysregulation from SGAs via its ability to reduce insulin resistance

Excessive heat accelerates medication breakdown and reduces effectiveness

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